Patricia Zancan Selected Research

Clotrimazole (Lotrimin)

12/2021	Clotrimazole presents anticancer properties against a mouse melanoma model acting as a PI3K inhibitor and inducing repolarization of tumor-associated macrophages.
11/2018	Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis.
1/2015	Nanomicellar Formulation of Clotrimazole Improves Its Antitumor Action toward Human Breast Cancer Cells.
1/2012	Clotrimazole preferentially inhibits human breast cancer cell proliferation, viability and glycolysis.

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Patricia Zancan Research Topics

Disease

16	Neoplasms (Cancer) 01/2022 - 05/2007
13	Breast Neoplasms (Breast Cancer) 01/2020 - 09/2008
3	Obesity 01/2022 - 03/2016
3	Insulin Resistance 01/2022 - 03/2016
3	Inflammation (Inflammations) 12/2021 - 09/2008
2	Melanoma (Melanoma, Malignant) 12/2021 - 11/2020
2	Glucose Intolerance 12/2021 - 03/2016
1	Hyperinsulinism (Hyperinsulinemia) 12/2021
1	Endometriosis 11/2018
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017
1	Body Weight (Weight, Body) 01/2017
1	Weight Gain 03/2016
1	Neoplasm Metastasis (Metastasis) 10/2015
1	Hypoxia (Hypoxemia) 05/2015
1	Diabetes Mellitus 01/2014
1	Chronic Disease (Chronic Diseases) 01/2014
1	Hyperglycemia 04/2010
1	Dysmenorrhea (Menstrual Pain) 09/2008
1	Acidosis 11/2007
1	Hemolysis 11/2005
1	Hemorrhage 01/2004
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2004
1	Thrombosis (Thrombus) 01/2004

Drug/Important Bio-Agent (IBA)

8	Pharmaceutical PreparationsIBA 12/2021 - 05/2007
6	EnzymesIBA 07/2021 - 04/2010
5	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 01/2009
4	Clotrimazole (Lotrimin)FDA LinkGeneric 12/2021 - 01/2012
4	Insulin (Novolin)FDA Link 12/2021 - 11/2005
3	Food Additives (Food Additive)IBA 12/2021 - 09/2008
3	TriazolesIBA 01/2019 - 01/2018
3	Adenosine Triphosphate (ATP)IBA 05/2015 - 05/2007
3	Phosphofructokinase-1 (Phosphofructokinase 1)IBA 06/2013 - 01/2009
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022 - 11/2020
2	Lactic Acid (Lactate)FDA LinkGeneric 12/2021 - 11/2007
2	Citric Acid (Citrate)FDA LinkGeneric 12/2021 - 03/2016
2	Salicylic Acid (2 Hydroxybenzoic Acid)FDA LinkGeneric 11/2020 - 01/2009
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 11/2020 - 01/2009
2	PhosphofructokinasesIBA 01/2017 - 10/2015
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2022
1	AlkaloidsIBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	IsoquinolinesIBA 01/2022
1	Conditioned Culture MediaIBA 12/2021
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2021
1	Heterocyclic Compounds (Compounds, Heterocyclic)IBA 07/2021
1	Adenylyl Cyclases (Adenylyl Cyclase)IBA 01/2020
1	Serotonin (5 Hydroxytryptamine)IBA 01/2020
1	lawsoneIBA 01/2019
1	XanthenesIBA 01/2019
1	Biological ProductsIBA 01/2019
1	NaphthoquinonesIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 01/2018
1	Cytostatic AgentsIBA 01/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018
1	MonosaccharidesIBA 01/2017
1	Mitogen-Activated Protein KinasesIBA 01/2017
1	Sucrose (Saccharose)IBA 03/2016
1	CytokinesIBA 03/2016
1	Drinking WaterIBA 03/2016
1	HexokinaseIBA 10/2015
1	Phosphotransferases (Kinase)IBA 05/2015
1	ResveratrolIBA 06/2013
1	Adenosine Diphosphate (ADP)IBA 06/2013
1	AzolesIBA 01/2012
1	Protein Isoforms (Isoforms)IBA 08/2010
1	Metformin (Glucophage)FDA LinkGeneric 04/2010
1	Ethanol (Ethyl Alcohol)IBA 09/2008
1	fucosylated chondroitin sulfateIBA 01/2004
1	GlycosaminoglycansIBA 01/2004
1	Heparin Cofactor IIIBA 01/2004
1	AnticoagulantsIBA 01/2004
1	Thrombin FDA Link 01/2004

Therapy/Procedure

3	Therapeutics 07/2021 - 01/2017
2	Drug Therapy (Chemotherapy) 01/2022 - 01/2018
1	Traditional Medicine (Folk Remedies) 01/2018
1	Mastectomy (Mammectomy) 10/2015